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And in 2021, the results from a series of five STEP trials (Semaglutide Treatment Effect in People with obesity) demonstrated marked weight loss even in individuals without type 2 diabetes (T2DM): Phase 3, for example, showed an average loss of about 15 percent over 68 weeks, more than double achieved by any prior obesity drug
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Starting with once-weekly injectable semaglutide (Ozempic) and dulaglutide (Trulicity) for diabetes, companies like Novo Nordisk and Lilly transformed these molecules into anti-obesity medicines (Wegovy, Zepbound) with unparalleled efficacy ( [18] ) ( [17] )
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